Question: My sister was diagnosed with FSGS. Though she is taking medicine, there is still too much protein in her urine. How to reduce it?
Answer: The primary concern for your sister is too much protein in urine. Proteinuria can speed up glomerulosclerosis so as to make her kidney condition worse.
Glomeruli are the filters in our kidneys and each kidney is composed of around one million glomeruli. In right condition, the glomeruli can filter out waste products and stop the leakage of useful substances into urine, like protein. However, now the glomeruli have been impaired so seriously and fail to prevent protein into urine.
As kidneys have powerful compensatory capacity, the residual glomeruli will do more work to filter the blood. That is why her creatinine has not increased yet. However, extra work will certainly accelerate renal function decline.
FSGS is a very serious kidney disease. Based on scientific date, around 25%-30% and 30-40% patients will step into kidney failure within in 5 and 10 years. The patients often do not respond well to the routine treatment.
To treat FSGS, we use external application of Chinese herbal medicines to treat FSGS. It works in the following treatment steps.
Dilate blood vessels: In FSGS, there is a large amount of immune complexes in glomerular capillaries. This will certainly cause local ischemia to renal intrinsic cells. By dilating blood vessels, it can improve the blood circulation in kidneys, thus relieving renal ischemia and anoxia. It also can create a favorable internal environment for repairing the impaired glomeruli.
Anti-inflammation: In FSGS, the glomeruli become inflamed and even necrotic. The effective medicines can decline the inflammatory factors into kidneys, thus declining further damage to kidney cells.
Anti-coagulation: On one hand, the inflammatory factors in blood can increase the viscosity of blood. On the other hand, loss of protein in urine also can elevate the lipid level in blood. Due to these two causes, thrombus is very likely to form in kidney blood vessels. By using the medicine of anti-coagulation, it can reduce the pressure to renal cells, thus creating a favorable environment for restoring the renal cells.
More importantly, Chinese medicines can stimulate the self-healing system of the body. Once the impaired renal cells can be restored, her renal function will be improved. Of course, the associated symptoms will also recover like protein in urine, edema.
At present, your sister is only on some medicines for controlling symptoms. But now the most important treatment goal now is to stop her renal function decline and restore the impaired renal cells.