Question: My mother with age 55 years is getting treated for last 5 years for familial FSGS and heavy proteinuria. Baseline creatinine was 1.6 for last 4 years. Now it has increased to 2.0. She is taking ace inhibitors medicines and blood pressure control medicines. Some immunosuppressants were also tried without much success. Is there any other treatment available which can at least stop the disease from progressing further?
Answer: FSGS is an immune-mediated kidney disorder. Due to immune disorder, a lot of immune complexes form in blood. These immune complexes then can deposit in kidneys with blood circulation, leading to inflammation of glomeruli. If the inflammation can not be controlled effectively in time, it will cause fibrosis and necrosis of glomeruli.
When the glomeruli become impaired, a lot of proteins will pass through them, ending up in urine. In return, heavy proteinuria can impair glomeruli significantly, so it is related to a very poor prognosis of FSGS.
Therefore, to treat FSGS effectively, three treatment steps will be involved:
1. Correct immune disorder and stop it from improper immune response. In this way, it will stop the production of immune complexes in blood.
2. Eliminate the immune depositing from kidneys. This is because immune deposits are the direct cause of inflammation of glomeruli.
3. Repair those impaired glomeruli and stop more from becoming affected adversely.
However, you can see that her current medicines only can help control certain symptoms.That is why they can not stop renal function from worsening at all.
As the largest kidney disease specialized hospital in China, we mainly use Chinese treatments to treat kidney disease. To treat FSGS, Chinese treatments have the following effects.
1. Prevent renal function from deteriorating
Chinese medicines are featured with dilating blood vessels, anti-inflammation, anti-coagulation and degrading extracellular matrix. They can stop the releasing of inflammatory factors and clear up harmful substances to kidneys. In this way, it can halt the renal function from deteriorating immediately and effectively.
2. Active the self-replication of renal functional cells
Chinese Medicine can activate the self-replication of renal functional cells and boost the reconstruction of kidney structure. The active materials in Chinese medicines can block renal fibrosis, dilate arteries at all levels, improve the regeneration and differentiation of renal functional cells. Meanwhile, the medicines can promote the secretion of growth factors so as to activate the formation of new blood vessels and accelerate the reconstruction of glomeruli.
3. Improve the metabolic disorders and provide an aerobic environment for repairing the impaired renal functional cells.
The effective medicines can dilate blood vessels at all levels and increase blood and oxygen supply to kidneys. In this way, it can create an aerobic environment for restoring the impaired kidneys. As renal ischemia and anoxia is the root cause of renal fibrosis, once these conditions are reversed, the kidney function will stop deteriorating.
4. Chinese medicines can provide essential substances for rebuilding kidney structure
Chinese medicines are rich in trace elements, organic acid, essential amino acid and vitamins. They can provide essential elements for restoring kidneys and also stimulate the body to synthesize necessary elements and substances.
5. Regulate immune function
Chinese medicines can enhance the phagocytic function of immune cells. In this way, they can restrain the immune inflammatory response and enhance immunity effectively and remarkably.
After the above systemic treatment, your mother's kidney function will stop deteriorating and have an improvement. Her creatinine level can reach a normal range.
Is there any treatment to stop FSGS from progressing further? Now you get the answer. If you are interested in the above treatment, please leave a message below or contact online doctor.