What Factors Are Associated with the Prognosis of IgA Nephropathy

What Factors Are Associated with the Prognosis of IgA Nephropathy
IgA Nephropathy is a chronic primary glomerular disease. It was once considered as a benign course. However, from the current observation, it can be seen that about 40% of the patients with IgA Nephropathy have gradually decreased renal function, and about half of the patients have reached end-stage renal failure 20 years after diagnosis. The prognosis is correlated with the following factors:

1. Gender

The disease occurs more frequently in men and is more severe than in women.

2. Age of onset

Early detection of the disease (before the age of 35) can prevent and slow the progression into renal failure after treatment such as hypertension control. Patients who detect the disease late and old patients usually have glomerular sclerosis, tubulointerstitial fibrosis and vascular lesions, so their prognosis is relatively poor.

3. Proteinuria

A large amount of proteinuria, or 24-hour urinary protein quantification > 2g, suggested that the glomerular lesions are more severe.

4. High blood pressure

High blood pressure often indicates the presence of vascular disease, which is parallel to extensive glomerular disease, with poor prognosis.

5. Degree of renal impairment

Prognosis is poor in patients with impaired renal function when the disease is found.

6. Pathological type

When renal pathology suggests that the affected area of glomerular cells is greater than 30% diffuse hyperplasia and sclerosis, a large number of crescents form, extensive hypoplasmic fibrosis and vascular sclerosis, and immunofluorescence shows a large amount of IgA deposition and C3 deposition in the capillary wall, prognosis is poor.

Iga nephropathy (nephritis) is a kind of chronic kidney disease. Besides the above factors, it is also closely related to the patient's physical condition, immunity, daily diet, health care and recuperation, etc.

What factors are associated with the prognosis of IgA Nephropathy? Now you have a clear mind. Though some factors can not be changed, such as gender, age and pathological type, you can take treatment to bring proteinuria and high blood pressure under control, and reduce the renal impairment as much as possible. In our hospital, we usually use a systemic treatment, Toxin-Removing Treatment for treatment. It can improve prognosis greatly. What treatment are you receiving now? You can leave your comment below. Our renal experts will contact you and give you personalized guidance.

Tag:IgA Nephropathy Basics      IgA Nephropathy      

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