4 Types of Primary Nephrotic Syndrome

4 Types of Primary Nephrotic SyndromeNephrotic Syndrome is a group of symptoms rather than a single disease. Its typical symptoms include massive proteinuria, hypoproteinemia, heavy swelling and hyperlipemia. this syndrome is classified into primary one, secondary one and inherited one. Today let’s have a look at primary Nephrotic Syndrome.

Primary Nephrotic Syndrome belongs to primary glomerular disease. There are four types, including Minimal Change Disease, Membranous Nephropathy, FSGS and IgA Nephropathy.

1. Typical symptoms

-Minimal Change Disease. It is common to see among children and teenagers. And it is difficult to diagnose the disease at the onset. Blood urine is often to be seen.

-Membranous Nephropathy. It is common to see among middle aged people. It is also difficult to diagnose at the onset. Its progression is usually slow. Renal venous thrombosis is often to be seen. Gross hematuria is rarely to be seen.

-FSGS. Most patients hardly notice that they get the disease. They mostly present Nephrotic Syndrome. Microscopic hematuria is also common to see. Without proper treatment, kidney function will decline gradually.

-IgA Nephropathy. Gross hematuria usually presents after catching respiratory tract infections. People at any age can get this disease. But it is common among male people at 20-30 years old. Its common manifestation is gross hematuria and proteinuria.

2. Influence on kidney function

-Minimal Change Disease. Most patents are sensitive to steroids. After treatment, the disease can get remission. But due to long-term steroid application, it is easy for patients to have dependence on steroids. Besides, infections and fatigue can trigger the disease, so its recurrence rate is very high. Frequent relapse can cause kidney damage easily. When FSGS occurs, its prognosis will be bad.

-Membranous Nephropathy. Most patients have massive proteinuria and swelling. Sometimes creatinine level increases. In such a case, you should attach importance to check whether your kidneys are damaged.

-FSGS. In the early stage, it is difficult for you to observe it, but you may have high blood pressure, acute renal injury and renal tubule function damage. In most cases, kidney function impairment is associated with continuous proteinuria (more than 3.5g per day).

-IgA Nephropathy. In general, about 23% patients can get remission. About 20% patients develop to ESRD in 10 years. And 30% patients present kidney function impairment. Blood pressure, creatinine and 24h urine protein play an important role in the progression of disease.

From the above, we can see that different types of Nephrotic Syndrome have different kidney damage. Therefore, when treating this disorder, we should consider the different character of pathology, and the severity of kidney damage. For more information on Nephrotic Syndrome, please leave a message below or contact online doctor.

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